Path ID: DB00250_MESH_D007918_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D003622 | dapsone | Drug |
| UniProt:A0A0F4ER22 | Dihydropteroate synthase (Mycobacterium lepromatosis) | Protein |
| GO:0046654 | tetrahydrofolate biosynthetic process | BiologicalProcess |
| GO:0009113 | purine nucleobase biosynthetic process | BiologicalProcess |
| GO:0071897 | DNA biosynthetic process | BiologicalProcess |
| GO:0051301 | cell division | BiologicalProcess |
| taxonomy:480418 | Mycobacterium lepromatosis | OrganismTaxon |
| MESH:D007918 | Leprosy | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dapsone | DECREASES ACTIVITY OF | Dihydropteroate Synthase (Mycobacterium Lepromatosis) |
| Dihydropteroate Synthase (Mycobacterium Lepromatosis) | POSITIVELY REGULATES | Tetrahydrofolate Biosynthetic Process |
| Tetrahydrofolate Biosynthetic Process | POSITIVELY REGULATES | Purine Nucleobase Biosynthetic Process |
| Purine Nucleobase Biosynthetic Process | POSITIVELY REGULATES | Dna Biosynthetic Process |
| Dna Biosynthetic Process | PART OF | Cell Division |
| Cell Division | OCCURS IN | Mycobacterium Lepromatosis |
| Mycobacterium Lepromatosis | CAUSES | Leprosy |
Reference: