Path ID: DB00240_MESH_D008179_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C021137 | alclometasone dipropionate | Drug |
| InterPro:SSF50353 | Cytokine | GeneFamily |
| CHEBI:18295 | histamine | ChemicalSubstance |
| UniProt:P04150 | Glucocorticoid receptor | Protein |
| InterPro:IPR001464 | Annexin | GeneFamily |
| InterPro:IPR001211 | Phospholipase A2 | GeneFamily |
| GO:0006954 | inflammatory response | BiologicalProcess |
| HP:0000969 | Edema | PhenotypicFeature |
| HP:0010783 | Erythema | PhenotypicFeature |
| HP:0040189 | Scaling skin | PhenotypicFeature |
| HP:0032152 | Keratosis pilaris | PhenotypicFeature |
| HP:0004334 | Dermal atrophy | PhenotypicFeature |
| CHEBI:25029 | leukotriene | ChemicalSubstance |
| MESH:D008179 | Discoid lupus erythematosus | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Alclometasone Dipropionate | POSITIVELY REGULATES | Glucocorticoid Receptor |
| Alclometasone Dipropionate | NEGATIVELY CORRELATED WITH | Cytokine |
| Alclometasone Dipropionate | NEGATIVELY CORRELATED WITH | Histamine |
| Cytokine | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Histamine | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Glucocorticoid Receptor | INCREASES ABUNDANCE OF | Annexin |
| Annexin | NEGATIVELY REGULATES | Phospholipase A2 |
| Phospholipase A2 | POSITIVELY CORRELATED WITH | Leukotriene |
| Leukotriene | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Edema |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Erythema |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Scaling Skin |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Keratosis Pilaris |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Dermal Atrophy |
| Edema | MANIFESTATION OF | Discoid Lupus Erythematosus |
| Erythema | MANIFESTATION OF | Discoid Lupus Erythematosus |
| Scaling Skin | MANIFESTATION OF | Discoid Lupus Erythematosus |
| Keratosis Pilaris | MANIFESTATION OF | Discoid Lupus Erythematosus |
| Dermal Atrophy | MANIFESTATION OF | Discoid Lupus Erythematosus |
Reference: