Path ID: DB00214_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C026116 | torsemide | Drug |
| UniProt:Q13621 | Solute carrier family 12 member 1 | Protein |
| GO:0006814 | sodium ion transport | BiologicalProcess |
| GO:0003092 | renal water retention | BiologicalProcess |
| HP:0032263 | Increased blood pressure | PhenotypicFeature |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Torsemide | DECREASES ACTIVITY OF | Solute Carrier Family 12 Member 1 |
| Solute Carrier Family 12 Member 1 | POSITIVELY REGULATES | Sodium Ion Transport |
| Sodium Ion Transport | REGULATES | Renal Water Retention |
| Renal Water Retention | POSITIVELY CORRELATED WITH | Increased Blood Pressure |
| Increased Blood Pressure | MANIFESTATION OF | Hypertensive Disorder |
Reference: