Path ID: DB00206_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D012110 | reserpine | Drug |
| UniProt:Q05940 | Synaptic vesicular amine transporter | Protein |
| reactome:R-HSA-181430 | Norepinephrine Neurotransmitter Release Cycle | Pathway |
| GO:0042310 | vasoconstriction | BiologicalProcess |
| HP:0032263 | Increased blood pressure | PhenotypicFeature |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Reserpine | NEGATIVELY REGULATES | Synaptic Vesicular Amine Transporter |
| Synaptic Vesicular Amine Transporter | PARTICIPATES IN | Norepinephrine Neurotransmitter Release Cycle |
| Norepinephrine Neurotransmitter Release Cycle | POSITIVELY CORRELATED WITH | Vasoconstriction |
| Vasoconstriction | POSITIVELY CORRELATED WITH | Increased Blood Pressure |
| Increased Blood Pressure | POSITIVELY CORRELATED WITH | Hypertensive Disorder |
Reference: