Path ID: DB00203_MESH_D007172_1

Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068677 | sildenafil | Drug |
| UniProt:O76074 | phosphodisterase type 5 | Protein |
| MESH:D006152 | cGMP | ChemicalSubstance |
| GO:0042311 | Vasodilation | BiologicalProcess |
| MESH:D007172 | Erectile Disfunction | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Sildenafil | DECREASES ACTIVITY OF | Phosphodisterase Type 5 |
| Phosphodisterase Type 5 | DECREASES ABUNDANCE OF | Cgmp |
| Cgmp | PARTICIPATES IN | Vasodilation |
| Vasodilation | NEGATIVELY CORRELATED WITH | Erectile Disfunction |
Reference: