Path ID: DB00196_MESH_D016919_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015725 | Fluconazole | Drug |
| UniProt:P10613 | Lanosterol 14-alpha demethylase (Candida albicans) | Protein |
| GO:0006696 | Ergosterol biosynthetic process | BiologicalProcess |
| GO:0042546 | Cell wall biogenesis | BiologicalProcess |
| taxonomy:5206 | Cryptococcus | OrganismTaxon |
| MESH:D016919 | Cryptococcal meningitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fluconazole | DECREASES ACTIVITY OF | Lanosterol 14-Alpha Demethylase (Candida Albicans) |
| Lanosterol 14-Alpha Demethylase (Candida Albicans) | POSITIVELY REGULATES | Ergosterol Biosynthetic Process |
| Ergosterol Biosynthetic Process | PRECEDES | Cell Wall Biogenesis |
| Cell Wall Biogenesis | OCCURS IN | Cryptococcus |
| Cryptococcus | CAUSES | Cryptococcal Meningitis |
Reference: