Path ID: DB00191_MESH_D007022_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D010645 | Phentermine | Drug |
| UniProt:P23975 | Sodium-dependent noradrenaline transporter | Protein |
| GO:0051620 | Norepinephrine uptake | BiologicalProcess |
| MESH:D009638 | Norepinephrine | ChemicalSubstance |
| GO:0004936 | Alpha-adrenergic receptor activity | BiologicalProcess |
| GO:0042310 | Vasoconstriction | BiologicalProcess |
| MESH:D007022 | Low blood pressure | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Phentermine | DECREASES ACTIVITY OF | Sodium-Dependent Noradrenaline Transporter |
| Sodium-Dependent Noradrenaline Transporter | PARTICIPATES IN | Norepinephrine Uptake |
| Norepinephrine Uptake | DECREASES ABUNDANCE OF | Norepinephrine |
| Norepinephrine | POSITIVELY REGULATES | Alpha-Adrenergic Receptor Activity |
| Alpha-Adrenergic Receptor Activity | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | NEGATIVELY CORRELATED WITH | Low Blood Pressure |
Reference: