Path ID: DB00182_MESH_D009765_1

db00182-mesh-d009765-1

Concepts

Identifier Name Type
MESH:D000661 Amphetamine Drug
UniProt:Q05940 Synaptic vesicular amine transporter Protein
GO:0098810 neurotransmitter reuptake BiologicalProcess
UniProt:Q96RJ0 Trace amine-associated receptor 1 Protein
UniProt:Q16568 Cocaine- and amphetamine-regulated transcript protein Protein
MESH:D009638 Norepinephrine ChemicalSubstance
MESH:D004298 Dopamine ChemicalSubstance
MESH:D009638 Norepinephrine ChemicalSubstance
MESH:D012701 Serotonin ChemicalSubstance
HP:0002591 Polyphagia PhenotypicFeature
MESH:D009765 Obesity Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Amphetamine DECREASES ACTIVITY OF Synaptic Vesicular Amine Transporter
Amphetamine NEGATIVELY REGULATES Neurotransmitter Reuptake
Amphetamine INCREASES ACTIVITY OF Trace Amine-Associated Receptor 1
Amphetamine INCREASES ACTIVITY OF Cocaine- And Amphetamine-Regulated Transcript Protein
Synaptic Vesicular Amine Transporter POSITIVELY REGULATES Neurotransmitter Reuptake
Trace Amine-Associated Receptor 1 NEGATIVELY REGULATES Neurotransmitter Reuptake
Cocaine- And Amphetamine-Regulated Transcript Protein NEGATIVELY CORRELATED WITH Polyphagia
Neurotransmitter Reuptake INCREASES ABUNDANCE OF Dopamine
Neurotransmitter Reuptake INCREASES ABUNDANCE OF Norepinephrine
Neurotransmitter Reuptake INCREASES ABUNDANCE OF Serotonin
Dopamine CORRELATED WITH Polyphagia
Norepinephrine CORRELATED WITH Polyphagia
Serotonin CORRELATED WITH Polyphagia
Polyphagia CONTRIBUTES TO Obesity

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