Path ID: DB00182_MESH_D009290_1

db00182-mesh-d009290-1

Concepts

Identifier Name Type
MESH:D000661 Amphetamine Drug
UniProt:Q05940 Synaptic vesicular amine transporter Protein
GO:0098810 neurotransmitter reuptake BiologicalProcess
UniProt:Q96RJ0 Trace amine-associated receptor 1 Protein
MESH:D009638 Norepinephrine ChemicalSubstance
MESH:D004298 Dopamine ChemicalSubstance
MESH:D009638 Norepinephrine ChemicalSubstance
MESH:D012701 Serotonin ChemicalSubstance
MESH:D009290 Narcolepsy Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Amphetamine DECREASES ACTIVITY OF Synaptic Vesicular Amine Transporter
Amphetamine NEGATIVELY REGULATES Neurotransmitter Reuptake
Amphetamine INCREASES ACTIVITY OF Trace Amine-Associated Receptor 1
Synaptic Vesicular Amine Transporter POSITIVELY REGULATES Neurotransmitter Reuptake
Trace Amine-Associated Receptor 1 NEGATIVELY REGULATES Neurotransmitter Reuptake
Neurotransmitter Reuptake INCREASES ABUNDANCE OF Dopamine
Neurotransmitter Reuptake INCREASES ABUNDANCE OF Norepinephrine
Neurotransmitter Reuptake INCREASES ABUNDANCE OF Serotonin
Dopamine CONTRIBUTES TO Narcolepsy
Norepinephrine CONTRIBUTES TO Narcolepsy
Serotonin CONTRIBUTES TO Narcolepsy

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