Path ID: DB00176_MESH_D009771_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D016666 | fluvoxamine | Drug |
| UniProt:P31645 | Sodium-dependent serotonin transporter | Protein |
| GO:0051610 | serotonin uptake | BiologicalProcess |
| GO:0043083 | Synaptic cleft | CellularComponent |
| GO:0060096 | Serotonin secretion, neurotransmission | BiologicalProcess |
| MESH:D009771 | Obsessive-compulsive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fluvoxamine | DECREASES ACTIVITY OF | Sodium-Dependent Serotonin Transporter |
| Sodium-Dependent Serotonin Transporter | NEGATIVELY REGULATES | Serotonin Uptake |
| Serotonin Uptake | LOCATED IN | Synaptic Cleft |
| Synaptic Cleft | CORRELATED WITH | Serotonin Secretion, Neurotransmission |
| Serotonin Secretion, Neurotransmission | NEGATIVELY CORRELATED WITH | Obsessive-Compulsive Disorder |
Reference: