Path ID: DB00153_MESH_D053098_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB00153 | ergocalciferol | Drug |
| CHEBI:86320 | 1α,25-dihydroxyvitamin D2 | ChemicalSubstance |
| UniProt:P11473 | Vitamin D3 receptor | Protein |
| GO:0070561 | vitamin D receptor signaling pathway | BiologicalProcess |
| GO:0030282 | bone mineralization | BiologicalProcess |
| MESH:D053098 | Familial x-linked hypophosphatemic vitamin D refractory rickets | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ergocalciferol | HAS METABOLITE | 1Α,25-Dihydroxyvitamin D2 |
| 1Α,25-Dihydroxyvitamin D2 | INCREASES ACTIVITY OF | Vitamin D3 Receptor |
| Vitamin D3 Receptor | POSITIVELY REGULATES | Vitamin D Receptor Signaling Pathway |
| Vitamin D Receptor Signaling Pathway | POSITIVELY REGULATES | Bone Mineralization |
| Bone Mineralization | NEGATIVELY CORRELATED WITH | Familial X-Linked Hypophosphatemic Vitamin D Refractory Rickets |
Reference: