Path ID: DB00136_MESH_D012080_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002117 | calcitriol | Drug |
| UniProt:P11473 | Vitamin D3 receptor | Protein |
| GO:0060558 | regulation of calcidiol 1-monooxygenase activity | BiologicalProcess |
| GO:0055074 | calcium ion homeostasis | BiologicalProcess |
| HP:0004363 | Abnormal circulating calcium concentration | PhenotypicFeature |
| MESH:D012080 | Renal osteodystrophy | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Calcitriol | INCREASES ACTIVITY OF | Vitamin D3 Receptor |
| Vitamin D3 Receptor | POSITIVELY REGULATES | Regulation Of Calcidiol 1-Monooxygenase Activity |
| Regulation Of Calcidiol 1-Monooxygenase Activity | POSITIVELY CORRELATED WITH | Calcium Ion Homeostasis |
| Calcium Ion Homeostasis | NEGATIVELY CORRELATED WITH | Abnormal Circulating Calcium Concentration |
| Abnormal Circulating Calcium Concentration | POSITIVELY CORRELATED WITH | Renal Osteodystrophy |
Reference: