Path ID: DB00108_MESH_D003424_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069442 | Natalizumab | Drug |
| UniProt:P13612 | Integrin alpha-4 | Protein |
| GO:0007159 | leukocyte cell-cell adhesion | BiologicalProcess |
| GO:0050900 | leukocyte migration | BiologicalProcess |
| GO:0006954 | inflammation | BiologicalProcess |
| MESH:D003424 | Crohn’s disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Natalizumab | MOLECULARLY INTERACTS WITH | Integrin Alpha-4 |
| Integrin Alpha-4 | PARTICIPATES IN | Leukocyte Cell-Cell Adhesion |
| Leukocyte Cell-Cell Adhesion | REGULATES | Leukocyte Migration |
| Leukocyte Migration | REGULATES | Inflammation |
| Inflammation | CAUSES | Crohn’S Disease |
Reference: