Path ID: DB00107_MESH_D006473_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D010121 | oxytocin | Drug |
| UniProt:P30559 | Oxytocin receptor | Protein |
| GO:0004990 | oxytocin receptor activity | MolecularActivity |
| GO:0070509 | transmembrane calcium influx | BiologicalProcess |
| GO:0004687 | myosin light chain kinase activity | MolecularActivity |
| GO:0070471 | uterine smooth muscle contraction | BiologicalProcess |
| MESH:D006473 | Postpartum hemorrhage | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Oxytocin | INCREASES ACTIVITY OF | Oxytocin Receptor |
| Oxytocin Receptor | PARTICIPATES IN | Oxytocin Receptor Activity |
| Oxytocin Receptor Activity | POSITIVELY REGULATES | Transmembrane Calcium Influx |
| Transmembrane Calcium Influx | POSITIVELY REGULATES | Myosin Light Chain Kinase Activity |
| Myosin Light Chain Kinase Activity | POSITIVELY REGULATES | Uterine Smooth Muscle Contraction |
| Uterine Smooth Muscle Contraction | NEGATIVELY CORRELATED WITH | Postpartum Hemorrhage |
Reference: