Path ID: DB00068_MESH_D020529_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068576 | Interferon beta-1b | Drug |
| UniProt:P17181 | Interferon alpha/beta receptor 1 | Protein |
| UniProt:P48551 | Interferon alpha/beta receptor 2 | Protein |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| GO:0042100 | B cell proliferation | BiologicalProcess |
| GO:0050798 | Activated T cell proliferation | BiologicalProcess |
| GO:0019882 | Antigen processing and presentation | BiologicalProcess |
| MESH:D020529 | Relapsing remitting multiple sclerosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Interferon Beta-1B | INCREASES ACTIVITY OF | Interferon Alpha/Beta Receptor 1 |
| Interferon Alpha/Beta Receptor 1 | NEGATIVELY REGULATES | Inflammatory Response |
| Interferon Alpha/Beta Receptor 1 | NEGATIVELY REGULATES | B Cell Proliferation |
| Interferon Alpha/Beta Receptor 1 | NEGATIVELY REGULATES | Activated T Cell Proliferation |
| Interferon Alpha/Beta Receptor 1 | NEGATIVELY REGULATES | Antigen Processing And Presentation |
| Interferon Beta-1B | INCREASES ACTIVITY OF | Interferon Alpha/Beta Receptor 2 |
| Interferon Alpha/Beta Receptor 2 | NEGATIVELY REGULATES | Inflammatory Response |
| Interferon Alpha/Beta Receptor 2 | NEGATIVELY REGULATES | B Cell Proliferation |
| Interferon Alpha/Beta Receptor 2 | NEGATIVELY REGULATES | Activated T Cell Proliferation |
| Interferon Alpha/Beta Receptor 2 | NEGATIVELY REGULATES | Antigen Processing And Presentation |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Relapsing Remitting Multiple Sclerosis |
| B Cell Proliferation | POSITIVELY CORRELATED WITH | Relapsing Remitting Multiple Sclerosis |
| Activated T Cell Proliferation | POSITIVELY CORRELATED WITH | Relapsing Remitting Multiple Sclerosis |
| Antigen Processing And Presentation | POSITIVELY CORRELATED WITH | Relapsing Remitting Multiple Sclerosis |
Reference: