Path ID: DB00063_MESH_D054058_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C086648 | Eptifibatide | Drug |
| UniProt:P05106 | Integrin beta-3 | Protein |
| UniProt:P08514 | Integrin alpha-IIb | Protein |
| GO:0072378 | Blood coagulation, fibrin clot formation | BiologicalProcess |
| GO:0008015 | Blood circulation | BiologicalProcess |
| GO:0070527 | Platelet aggregation | BiologicalProcess |
| MESH:D054058 | Acute coronary syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Eptifibatide | DECREASES ACTIVITY OF | Integrin Beta-3 |
| Eptifibatide | DECREASES ACTIVITY OF | Integrin Alpha-Iib |
| Integrin Beta-3 | POSITIVELY REGULATES | Platelet Aggregation |
| Integrin Alpha-Iib | POSITIVELY REGULATES | Platelet Aggregation |
| Platelet Aggregation | POSITIVELY CORRELATED WITH | Blood Coagulation, Fibrin Clot Formation |
| Blood Coagulation, Fibrin Clot Formation | NEGATIVELY REGULATES | Blood Circulation |
| Blood Circulation | NEGATIVELY CORRELATED WITH | Acute Coronary Syndrome |
Reference: