Path ID: DB00046_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D061268 | insulin lispro | Drug |
| UniProt:P06213 | Insulin receptor | Protein |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | MolecularActivity |
| MESH:D055504 | Insulin Receptor Substrate Proteins | GeneFamily |
| GO:0046323 | glucose import | BiologicalProcess |
| MESH:D003924 | Diabetes mellitus type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Insulin Lispro | INCREASES ACTIVITY OF | Insulin Receptor |
| Insulin Receptor | POSITIVELY REGULATES | Transmembrane Receptor Protein Tyrosine Kinase Activity |
| Transmembrane Receptor Protein Tyrosine Kinase Activity | POSITIVELY REGULATES | Insulin Receptor Substrate Proteins |
| Insulin Receptor Substrate Proteins | POSITIVELY REGULATES | Glucose Import |
| Glucose Import | NEGATIVELY CORRELATED WITH | Diabetes Mellitus Type 2 |
Reference: