Path ID: DB00022_MESH_D019698_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C417083 | peginterferon alfa-2b | Drug |
| UniProt:P17181 | Interferon alpha/beta receptor 1 | Protein |
| UniProt:P48551 | Interferon alpha/beta receptor 1 | Protein |
| reactome:R-HSA-8950505 | Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | Pathway |
| GO:0140374 | antiviral innate immune response | BiologicalProcess |
| taxonomy:11103 | Hepacivirus C | OrganismTaxon |
| MESH:D019698 | Hepatitis C, Chronic | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Peginterferon Alfa-2B | INCREASES ACTIVITY OF | Interferon Alpha/Beta Receptor 1 |
| Peginterferon Alfa-2B | INCREASES ACTIVITY OF | Interferon Alpha/Beta Receptor 1 |
| Interferon Alpha/Beta Receptor 1 | POSITIVELY REGULATES | Gene And Protein Expression By Jak-Stat Signaling After Interleukin-12 Stimulation |
| Interferon Alpha/Beta Receptor 1 | POSITIVELY REGULATES | Gene And Protein Expression By Jak-Stat Signaling After Interleukin-12 Stimulation |
| Gene And Protein Expression By Jak-Stat Signaling After Interleukin-12 Stimulation | POSITIVELY REGULATES | Antiviral Innate Immune Response |
| Antiviral Innate Immune Response | CAUSED BY | Hepacivirus C |
| Hepacivirus C | CAUSES | Hepatitis C, Chronic |
Reference: