Path ID: DB00008_MESH_D019698_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C100416 | peginterferon alfa-2a | Drug |
| UniProt:P17181 | Interferon alpha/beta receptor 1 | Protein |
| GO:0007259 | receptor signaling pathway via JAK-STAT | BiologicalProcess |
| reactome:R-HSA-1169410 | Antiviral mechanism by IFN-stimulated genes | Pathway |
| GO:0140374 | antiviral innate immune response | BiologicalProcess |
| taxonomy:11103 | Hepacivirus C | OrganismTaxon |
| MESH:D019698 | Chronic hepatitis C | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Peginterferon Alfa-2A | POSITIVELY REGULATES | Interferon Alpha/Beta Receptor 1 |
| Interferon Alpha/Beta Receptor 1 | PARTICIPATES IN | Receptor Signaling Pathway Via Jak-Stat |
| Receptor Signaling Pathway Via Jak-Stat | POSITIVELY REGULATES | Antiviral Mechanism By Ifn-Stimulated Genes |
| Antiviral Mechanism By Ifn-Stimulated Genes | PART OF | Antiviral Innate Immune Response |
| Antiviral Innate Immune Response | IN TAXON | Hepacivirus C |
| Hepacivirus C | CAUSES | Chronic Hepatitis C |
Reference: