Path ID: DB00005_MESH_D001172_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068800 | Etanercept | Drug |
| UniProt:P01375 | Tumor necrosis factor | Protein |
| reactome:R-HSA-75893 | TNF signaling | Pathway |
| GO:0006954 | Inflammation | BiologicalProcess |
| HP:0002829 | Joint pain | PhenotypicFeature |
| HP:0001386 | Joint swelling | PhenotypicFeature |
| MESH:D001172 | Rheumatoid arthritis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Etanercept | DECREASES ACTIVITY OF | Tumor Necrosis Factor |
| Tumor Necrosis Factor | PARTICIPATES IN | Tnf Signaling |
| Tnf Signaling | POSITIVELY REGULATES | Inflammation |
| Inflammation | POSITIVELY REGULATES | Joint Pain |
| Inflammation | POSITIVELY REGULATES | Joint Swelling |
| Joint Pain | MANIFESTATION OF | Rheumatoid Arthritis |
| Joint Swelling | MANIFESTATION OF | Rheumatoid Arthritis |
| Inflammation | CAUSES | Rheumatoid Arthritis |
Reference: